Dr.Wasfi Dhahir
السبت، 7 يوليو 2018
الأحد، 7 يناير 2018
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السبت، 12 نوفمبر 2016
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Reproduction
Reproduction
By
Wasfi
Dhahir Abid Ali
Reproduction is the natural process among organisms by which
new individuals are generated and the species perpetuated. The reproduction of
organisms by the union of male and female reproductive cells (gametes) is
called sexual reproduction. While the reproduction in which offspring
are produced by a single parent, without the union of reproductive cells, is
called asexual reproduction.
spermatogenesis
The development of mature spermatozoa from
spermatogonia; it includes spermatocytogenesis and spermiogenesis. Also can be defined
as the entire process by which
spermatogonial stem cells divide and differentiate into sperms.
Oogenesis
The developmental
process by which the mature human ovum (the female reproductive cell) is
formed. Formation begins during the first 3 months of female embryonic life
with the development of ovarian follicles. Each follicle contains one oogonium
which, through the process of mitosis, becomes a primary oocyte containing 46
chromosomes. The oocyte then undergoes the first meiotic reduction division,
resulting in formation of a secondary oocyte and a polar body, each containing
22 autosomes (half the number of chromosomes that are found in nongerm cells)
and one X heterosome. Further division is arrested in prophase until the female
reaches puberty. The second meiotic division begins at ovulation and reaches
metaphase where, once again, division is arrested until the ovum is fertilized.
The second meiotic division is completed at fertilization, ending with
formation of the mature haploid ovum and one polar body.
Embryogenesis
Is the process by which
the embryo forms and develops. In mammals, the term refers chiefly to early
stages of prenatal development, whereas the terms fetus and fetal development
describe later stages.
Embryogenesis starts
with the fertilization of the egg cell (ovum) by a sperm cell, (spermatozoon).
Once fertilized, the ovum is referred to as a zygote, a single diploid cell.
The zygote undergoes mitotic divisions with no significant growth (a process
known as cleavage) and cellular differentiation, leading to development of a
multicellular embryo.
Fertilization and the
zygote
The egg cell is
generally is covered with protective envelopes, with different layers made of
glycoproteins and is known as the vitelline membrane (zona pellucida in
mammals). Fertilization (also known as 'conception', 'fecundation' and
'syngamy') is the process involves a sperm fusing with an ovum, which
eventually leads to the development of an embryo. The fertilized egg cell is
known as the zygote.
Cleavage and morula
Cell division with no significant
growth, producing a cluster of cells that is the same size as the original
zygote, is called cleavage. At least four initial cell divisions occur,
resulting in a dense ball of at least sixteen cells called the morula. The end
of cleavage is known as midblastula transition .
Formation of the
blastula
After the 7th cleavage
has produced 128 cells, the embryo is called a blastula. The blastula is
usually a spherical layer of cells characterized by an inner cell mass that is
distinct from the surrounding blastula.
Gastrulation
During gastrulation
cells migrate to the interior of the blastula, subsequently forming three
(triploblastic) germ layers. The embryo during this process is called a
gastrula. The germ layers are referred to as the ectoderm, mesoderm and
endoderm.
Nurolation
Formation of the early
nervous system - neural groove, tube and notochord>
Gonad differentiation
Humans, many mammals,
insects and other animals have an XY sex-determination system. Humans have
forty-six chromosomes, including two sex chromosomes, XX in females and XY in
males. It is obvious that the Y chromosome must carry at least one essential
gene which determines testicular formation (originally termed TDF). A gene in
the sex-determining region of the short arm of the Y, now referred to as SRY,
has been found to direct production of a protein, testis determining factor,
which binds to DNA, inducing differentiation of cells derived from the genital
ridges into testes.
a fetus is sexually
undifferentiated, or“noncommittal” as to which sex it will become. Its gonads begin
to develop at 5 to 6 weeks .Adjacent to each gonadal ridge are two ducts,
1- The mesonephric (wolfian)
2- The paramesonephric
(müllerian) duct.
In males, the mesonephric
ducts develop into the reproductive tract
and the paramesonephric
ducts degenerate.
The
Y chromosome has a gene called SRY(sex-determining region of the Y) that codes
for a protein called testis-determining factor (TDF).TDF then interacts with
genes on some of the other chromosomes, including a gene on the X chromosome
for androgen receptors, and those genes initiate the development of male
anatomy.
By8 to 9 weeks, the male has an identifiable
testis that begins to secrete testosterone. Each testis stimulates the mesonephric
duct on its own side to develop into the system of male reproductive ducts and atrophy of the paramesonephric (müllerian)
duct on that side.
السبت، 8 أكتوبر 2016
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